What can the PrenaTest® detect in my child?
The PrenaTest® can detect certain changes to chromosomes, so-called chromosomal disorders, in your unborn child. These are the trisomies 21, 18 und 13, Klinefelter syndrome and turner syndrome as well as triple X syndrome and XYY syndrome. With the PrenaTest®, you can individually decide which chromosome disorders you would like to test for. For example, you can test your child only for trisomy 21 or for the three trisomies 21, 18 and 13. Talk to your doctor about which tests are advisable for you in your personal situation. Incidentally: If desired, you can also learn whether you are expecting a girl or a boy.
What is the PrenaTest® unable to detect in my child?
The PrenaTest® cannot be used to determine structural changes to chromosomes. In these cases, for example, a piece of a chromosome is missing, there is an extra piece or a piece was incorporated incorrectly in the chromosome. So-called “mosaics” can also not be definitively determined. In a mosaic, cells of a tissue or of the entire organism of the embryo have different genetic information. In addition, despite performing the PrenaTest® with utmost care, there may be no or an unclear test result. It may then be necessary to repeat the test. We may then need a new blood sample from you. It is important for you to know that this does not reveal anything about the health of your child.
How safe is the PrenaTest®?
In studies to assess the accuracy of the PrenaTest® in single pregnancies, a correct result was determined in 99.8% of all blood samples. This means that out of 1000 blood samples tested, only two results were not correct. The accuracy of the PrenaTest® was also verified in twin pregnancies. The result was correct in all blood samples tested. Since there were no cases with trisomy 13 or 18 in these studies, there are still no scientific data on this (Feb. 2014). The accuracy of the PrenaTest® to determine numerical maldistributions of the sex chromosomes (X and Y) was also investigated in clinical studies. It is currently less accurate than the PrenaTest® in the case of trisomies 21, 18 and 13 and may vary, depending on the chromosomal disorder tested.