PrenaTest® Patient profile

For which patients is the PrenaTest® suitable?

National and international professional organizations recommend NIPT as a primary diagnostic procedure in combination with ultrasound in expectant mothers with an increased risk of fetal aneuploidies, i.e. in women of advanced age or with twin pregnancies, and as a follow-up test following a positive first-trimester screening (FTS). The PrenaTest® is also suitable for high-risk pregnancies which are already beyond the FTS time frame.


In order to undergo the PrenaTest®, one of the following indications must apply to the expectant mother:
    • Age 35 years and over at the time of the birth of the child
    • Increased risk of aneuploidy based on screening methods for prenatal risk determination
    • Ultrasound anomalies of the fetus
    • Prior pregnancy with fetal aneuploidy
    • Hereditary risk of fetal aneuploidy
    • Other medical reasons (joint decision of physician and patient)

“The PrenaTest® offers a valuable improvement for expectant mothers, especially in the case of multi-fetal pregnancies, by reducing the false-positive rate (FPR) to below 1% as compared to the FPR for twins at the first-trimester screening which is 10–15%. This can eliminate the need for invasive diagnostics and the associated risks for many women pregnant with twins.”

Dr. med. Markus Weber Specialist in gynecology and obstetrics,
Praxis für Pränatalmedizin (DEGUM II), Steinfurt
(a prenatal practice in Germany)
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