PrenaTest®

PrenaTest® gives clarity

The PrenaTest® provides you with a test method that combines many of the advantages of the conventional methods with none of the disadvantages. On the one hand, the PrenaTest® is safe for your unborn child while on the other hand, it determines very accurately whether or not any of the specified chromosomal disorders is present.

 

What can the PrenaTest® detect in my child?

The PrenaTest® is known as a non-invasive prenatal test (NIPT). From maternal blood, it can detect the following changes in the genetic material of your unborn child, known as chromosomal disorders:

 

  •  Trisomy 21 (Down syndrome)
  • Trisomy 18 (Edwards syndrome)
  • Trisomy 13 (Patau syndrome)
  • Maldistributions of the sex chromosomes X and Y (Turner, triple X, Klinefelter and XYY syndrome)
  • 22q11.2 microdeletion (DiGeorge syndrome)

If desired, you can also learn whether you are expecting a girl or a boy. In Germany, in accordance with statutory provisions, your doctor will tell you the sex of your child starting from the twelfth week of pregnancy post-conception. National regulations in other countries may vary.

 

What is the PrenaTest® unable to detect in my child?

Certain special forms of chromosomal disorders, for example, structural changes to chromosomes or mosaics, cannot be detected. In the case of structural chromosomal disorders, a piece of a chromosome is missing, there is an extra piece or a piece was incorporated incorrectly in the chromosome. In a mosaic, cells of a tissue or of the entire organism of the embryo have different genetic information.

 

How accurate is the PrenaTest®?

The high degree of accuracy of the PrenaTest® has been proven in many clinical studies. In addition, the test was approved by an independent inspection body which acts on behalf of public authorities. The studies show that in 99.8% of all blood samples from single pregnancies, the test results of the PrenaTest® for the determination of trisomies 13,18 and 21 were correct. This means that out of 1000 blood samples tested, 998 results were correctly determined. The test quality was also verified in the case of twin pregnancies. Here as well, the result was correct for all blood samples tested. The accuracy of the PrenaTest® to detect maldistributions of sex chromosomes (X/Y) is somewhat lower than for the detection of trisomies 13,18 and 21. In another clinical study, the 22q11.2 microdeletion was also correctly detected in all blood samples.

 

It is important for you to know that 100% accuracy in the use of non-invasive prenatal tests should not be expected. In rare cases, there may be no or an unclear test result. However, this does not indicate anything about the health of your child. You may then repeat the test at no additional charge Please contact your doctor for comprehensive information and advice.

 

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